NVR 3 778

Drug Profile

NVR 3 778

Alternative Names: AL-3778; ALS-003778; JNJ-63595948; NVR-1221; NVR-3-778

Latest Information Update: 31 Oct 2017

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At a glance

  • Originator Novira Therapeutics
  • Class Antivirals; Small molecules
  • Mechanism of Action Capsid protein inhibitors; Viral core protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Hepatitis B

Most Recent Events

  • 16 Oct 2017 Alios Biopharma terminates a phase I trial due to sponsor's decision for Hepatitis B (In volunteers) in New Zealand (PO, Capsule, Tablet) (NCT03032536)
  • 16 Oct 2017 Novira withdraws a phase IIa trial prior to enrolment for Chronic Hepatitis B virus (HBV) infection (Combination therapy, Treatment naive) as per Sponsor's decision in Mauritius (NCT03125213)
  • 31 Jan 2017 Phase-I clinical trials in Hepatitis B (In volunteers) in New Zealand (PO, Tablet) (NCT03032536)
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