Drug Profile


Alternative Names: FPI-01; SLS-001; WT-1 analog peptide vaccine; WT1 cancer vaccine - SELLAS Life Sciences; WT1 peptide vaccine - Memorial Sloan Kettering; WT1 vaccine - Memorial Sloan Kettering; ZELTHERVA

Latest Information Update: 21 Sep 2017

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At a glance

  • Originator Memorial Sloan-Kettering Cancer Center
  • Developer Advaxis; Memorial Sloan-Kettering Cancer Center; Sellas Life Sciences Group
  • Class Cancer vaccines; Peptide vaccines; Peptides
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mesothelioma; Acute myeloid leukaemia
  • New Molecular Entity No

Highest Development Phases

  • Phase II Acute lymphoblastic leukaemia; Acute myeloid leukaemia; Mesothelioma
  • Phase I/II Multiple myeloma; Ovarian cancer
  • Phase I Fallopian tube cancer; Peritoneal cancer
  • Research Cancer

Most Recent Events

  • 02 Oct 2017 SELLAS Life Sciences plans a phase I/II trial for Haematological malignancies and Solid tumours in first half of 2018
  • 14 Sep 2017 Interim efficacy and immunogenicity data from a phase II trial in Mutliple myeloma released by SELLAS Life Sciences
  • 01 Mar 2017 SELLAS Life Sciences plans a phase III trial for Acute myeloid leukaemia
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