Research programme: antibody-based therapeutics - BioAtla

Drug Profile

Research programme: antibody-based therapeutics - BioAtla

Alternative Names: CAB anti-AXL ADC; CAB-ADC; CAB-Axl antibodies; CAB-Axl antibody-drug conjugates; CAB-Axl-ADC

Latest Information Update: 10 Mar 2017

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At a glance

  • Originator BioAtla
  • Class Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action Axl receptor tyrosine kinase inhibitors; Cytokine inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Autoimmune disorders; Cancer; Colorectal cancer; Crohn's disease; Haematological malignancies; Non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Ulcerative colitis

Most Recent Events

  • 06 Dec 2016 BioAtla and Beijing Sinobioway select four CAB product programs for development with undisclosed target indications
  • 16 Apr 2016 Preclinical trials in Cancer in USA (Parenteral) before April 2016
  • 14 Apr 2016 Pharmacodynamics and adverse events data from preclincial studies in Cancer presented at the 107th Annual Meeting of the American Association for Cancer Research (AACR-2016)
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