Fluciclovine 18F

Drug Profile

Fluciclovine 18F

Alternative Names: 18F-FACBC; 18F fluciclovine; Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic-acid; Anti-1-amino-3-fluorine-18-fluorocyclobutane-1-carboxylic acid; Anti-18-F-FACBC; Anti-3-18F-FACBC; Anti-F-18-fluorocyclobutane-carboxylic-acid; Axumin; FACBC; NMK-36

Latest Information Update: 30 Mar 2017

Price : $50

At a glance

  • Originator Emory University
  • Developer Blue Earth Diagnostics; Emory University; GE Healthcare; Memorial Sloan-Kettering Cancer Center; Nihon Medi-Physics
  • Class Amino acids; Carboxylic acids; Cyclobutanes; Imaging agents; Radiopharmaceuticals; Small molecules
  • Mechanism of Action Positron-emission tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Prostate cancer
  • Phase III Glioma
  • Clinical Phase Unknown Brain cancer; Breast cancer; Head and neck cancer
  • No development reported Lung cancer; Parathyroid cancer

Most Recent Events

  • 30 Mar 2017 Nihon Medi-Physics completes a phase III trial for Glioma (Diagnosis) in Japan (JapicCTI-152986)
  • 23 Mar 2017 Committee for Medicinal Products for Human Use (CHMP) recommends approval of fluciclovine 18F for Prostate cancer (Diagnosis) in European Union
  • 15 Feb 2017 Clinical trials in Breast cancer (Diagnosis, In adults, In the elderly) in United Kingdom (IV) (NCT03036943)
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