Lumbricus rubellus extract

Drug Profile

Lumbricus rubellus extract

Alternative Names: Disolf; DLBS-1033; Lumbricus low molecular weight proteins; Red earthworm extract

Latest Information Update: 23 May 2017

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At a glance

  • Originator Dexa Medica
  • Class Alternative medicine; Enzymes; Thrombolytics; Traditional-Chinese-medicine
  • Mechanism of Action Fibrin inhibitors; Fibrinogen inhibitors; Fibrinolysis stimulants; Fibrinolytic agents; Janus kinase 1 inhibitors; Matrix metalloproteinase 9 inhibitors; NF-kappa B inhibitors; Platelet aggregation inhibitors; STAT1 transcription factor inhibitors; Tumour necrosis factor alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Stroke
  • Phase II/III Acute coronary syndromes; Peripheral arterial disorders

Most Recent Events

  • 12 Feb 2017 Dexa Medica terminates a phase III trial in Stroke (Adjunctive treatment) in Indonesia (PO) (NCT02362984)
  • 15 Dec 2016 Biomarkers information updated
  • 01 Nov 2016 Phase-II/III clinical trials in Acute coronary syndromes in Indonesia (PO) (NCT02976701)
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