Drug Profile


Alternative Names: 314d; APS-314d; Beraprost Sodium 314d Modified Release; Beraprost-314d; BPS-314d-MR; L-314d-QID

Latest Information Update: 27 Sep 2017

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At a glance

  • Originator Toray
  • Developer Lung Biotechnology
  • Class 3-ring heterocyclic compounds; Alkynes; Antiplatelets; Benzofurans; Butyric acids; Cyclopentanes; Prostaglandins; Small molecules; Vasodilators
  • Mechanism of Action Epoprostenol receptor agonists; Platelet aggregation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase III Pulmonary arterial hypertension

Most Recent Events

  • 27 Sep 2017 Esuberaprost is still in phase III trials for Pulmonary arterial hypertension in USA and Israel (NCT01908699)
  • 27 Jul 2017 United Therapeutics completes enrolment in a phase-III clinical trial in Pulmonary arterial hypertension in USA prior to July 2017 (PO) (NCT01908699; 9220286)
  • 30 May 2013 Phase-III clinical trials in Pulmonary arterial hypertension in USA (PO) (NCT01908699)
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