Flotetuzumab

Drug Profile

Flotetuzumab

Alternative Names: CD123 x CD3; MGD 006; MGD006/S80880; S 80880

Latest Information Update: 14 Sep 2017

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At a glance

  • Originator MacroGenics
  • Developer MacroGenics; Servier
  • Class Antineoplastics; Bispecific antibodies; Monoclonal antibodies
  • Mechanism of Action CD3 antigen inhibitors; Immunomodulators; Interleukin-3-receptor-alpha-subunit-antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 11 Sep 2017 Interim safety and efficacy data from a phase I trial in Acute myeloid leukaemia and Myelodysplastic syndromes presented at the Annual Congress of European Society for Medical Oncology (ESMO-2017)
  • 05 Jun 2017 Phase-I clinical trials in Acute myeloid leukaemia (Recurrent, Second-line therapy or greater, Treatment-resistant) in Germany, Netherlands (Parenteral), before June 2017
  • 05 Jun 2017 Phase-I clinical trials in Myelodysplastic syndromes (Second-line therapy or greater) in Netherlands, Germany (Parenteral), before June 2017
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