Drug Profile


Alternative Names: PXT 864

Latest Information Update: 27 Sep 2017

Price : *
* Final gross price and currency may vary according to local VAT and billing address.

At a glance

  • Originator BioSystems International; INSERM; Pharnext; University of Bordeaux
  • Developer Pharnext
  • Class Alkanesulfonic-acids; Aminobutyric acids; Antiparkinsonians; Antispastics; Muscle relaxants; Nootropics; Small molecules
  • Mechanism of Action GABA B receptor agonists; GABA receptor agonists; Glutamate receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Alzheimer's disease
  • Phase I Amyotrophic lateral sclerosis; Parkinson's disease
  • Discontinued Memory disorders

Most Recent Events

  • 26 Sep 2017 PXT 864 is still in phase II trials for Alzheimer's disease in France (Pharnext website, September 2017)
  • 16 Jul 2017 Efficacy and adverse events data from the phase II PLEODIAL trial in Alzheimer's disease presented at the Alzheimer's Association International Conference 2017 (AAIC-2017)
  • 26 May 2017 Chemical structure information added
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at so we can help.

Back to top