Tc-99m-annexin V-128

Drug Profile

Tc-99m-annexin V-128

Alternative Names: 99mTc-rhAnnexin V-128; 99mTechnetium-labelled rhAnnexin V-128; Tc-99m-recombinant human annexin V-128; Tc-99m-rhAnnexin V-128

Latest Information Update: 22 Jul 2017

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At a glance

  • Originator Atreus Pharmaceuticals
  • Developer Advanced Accelerator Applications; INSERM
  • Class Calcium binding proteins; Organotechnetium compounds; Radiopharmaceutical diagnostics; Radiopharmaceuticals; Technetium compounds
  • Mechanism of Action Single-photon emission-computed tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Cardiomyopathies; Carotid stenosis
  • Phase I/II Ankylosing spondylitis; Cardiovascular disorders; Rheumatoid arthritis
  • Preclinical Autoimmune disorders; Cancer

Most Recent Events

  • 01 Aug 2017 Advanced Accelerator Applications plans a phase II trial for Spondyloarthritis (Diagnosis) (NCT03232580)
  • 14 Jun 2017 Interim pharmacodynamic data from preclinical studies in Autoimmune disorders (diagnosis) presented at the 18th Annual Congress of the European League Against Rheumatism (EULAR-2017)
  • 16 Jul 2016 No recent reports of development identified for phase-I development in Rheumatoid-arthritis(Diagnosis, In volunteers) in Canada (IV, Injection)
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