Drug Profile


Alternative Names: Ang2 Antibody co-formulated with aflibercept; Ang2 antibody/aflibercept; Ang2 antibody/Eylea; Nesvacumab/aflibercept; REGN 910-3

Latest Information Update: 10 Sep 2017

Price : *
* Final gross price and currency may vary according to local VAT and billing address.

At a glance

  • Originator Regeneron Pharmaceuticals
  • Class Eye disorder therapies; Monoclonal antibodies; Recombinant fusion proteins
  • Mechanism of Action Angiogenesis inhibitors; Angiopoietin-2 inhibitors; Placenta growth factor inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Diabetic macular oedema; Wet age-related macular degeneration

Most Recent Events

  • 10 Feb 2017 Regeneron completes enrolment in the ONYX trial in Wet-age related macular degeneration in USA
  • 10 Feb 2017 Regeneron completes enrolment in the RUBY trial in Diabetic macular oedema in USA
  • 24 Mar 2016 Aflibercept/nesvacumab licensed to Bayer worldwide, except USA, for the treatment of Eye disorders
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at so we can help.

Back to top