Drug Profile


Alternative Names: Anti-Ebola monoclonal antibody - Mapp Pharmaceuticals; ZMapp

Latest Information Update: 17 Oct 2016

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At a glance

  • Originator Mapp Biopharmaceutical; Public Health Agency of Canada
  • Developer Mapp Biopharmaceutical; National Institute of Allergy and Infectious Diseases
  • Class Monoclonal antibodies; Recombinant fusion proteins
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Ebola virus infections

Most Recent Events

  • 12 Oct 2016 Safety data from the PREVAIL II phase I/II trial in Ebola virus infections released by Mapp Biopharmaceuticals
  • 23 Feb 2016 Efficacy data from a phase I/II trial in Ebola virus infections released by Leaf Biopharmaceutical
  • 23 Feb 2016 Leaf Biopharmaceutical completes a phase I/II trial in Ebola virus infections in USA, Sierra Leone, Liberia and Guinea (IV) (NCT02363322)
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