JCAR 017

Drug Profile

JCAR 017

Alternative Names: 4-1BB-modified CAR CD8+ and CD4+ T lymphocyte therapy - Juno Therapeutics; anti-CD19-EGFRt-4-1BB-zeta modified CAR CD8+ and CD4+ T lymphocyte therapy - Juno Therapeutics; anti-CD19/EGFRt/4-1BB/zeta modified CAR CD8+ and CD4+ T lymphocyte therapy - Juno Therapeutics; JCAR017

Latest Information Update: 09 Feb 2017

Price : $50

At a glance

  • Originator Juno Therapeutics
  • Developer Juno Therapeutics; Seattle Children's Hospital
  • Class Cancer vaccines; CAR-T cell therapies
  • Mechanism of Action Cytotoxic T lymphocyte stimulants; Gene transference; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Leukaemia
  • Phase I Non-Hodgkin's lymphoma

Most Recent Events

  • 20 Dec 2016 JCAR 017 receives Breakthrough Therapy status for Non-Hodgkin's lymphoma (Second-line therapy or greater) in USA
  • 20 Dec 2016 The EMA designates PRIME status to JCA R017 for the treatment of Non-Hodgkin's lymphoma (Second-line therapy) in European Union
  • 05 Dec 2016 Phase-II clinical trials in Leukaemia (In adolescents, In children, In infants, Second-line therapy or greater, In adults) in USA (IV)
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