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Cofetuzumab pelidotin - Abbvie/Pfizer

Drug Profile

Cofetuzumab pelidotin - Abbvie/Pfizer

Alternative Names: ABBV-647; PF-06647020; PF-6647020; PF-7020; PTK7-ADC

Latest Information Update: 06 Feb 2024

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At a glance

  • Originator Stemcentrx
  • Developer AbbVie; Pfizer; Stemcentrx
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Non-small cell lung cancer; Solid tumours; Triple negative breast cancer

Most Recent Events

  • 06 Feb 2024 Discontinued - Phase-I for Solid tumours (Late-stage disease, Second-line therapy or greater) in Spain (IV) prior to February 2024
  • 02 Feb 2024 Discontinued - Phase-I for Non-small cell lung cancer (Recurrent, Second-line therapy or greater) in Japan, Israel, Taiwan, Spain, South Korea (IV) prior to February 2024
  • 02 Feb 2024 Discontinued - Phase-I for Solid tumours (Late-stage disease, Second-line therapy or greater) in USA (IV) prior to February 2024
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