Cofetuzumab pelidotin

Drug Profile

Cofetuzumab pelidotin

Alternative Names: PF-06647020; PF-6647020; PTK7-ADC

Latest Information Update: 12 Apr 2017

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At a glance

  • Originator Stemcentrx
  • Developer Pfizer; Stemcentrx
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates
  • Mechanism of Action PTK7 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 14 Aug 2017 Indiana University plans a phase I trial for Breast cancer (Metastatic disease, Second-line therapy or greater, Combination therapy) in USA (NCT03243331)
  • 10 Apr 2017 Pfizer re-initiates enrolment in a phase I trial in Solid tumours (Late-stage disease, Second-line therapy or greater) in Spain and USA (IV) (NCT02222922)
  • 07 Oct 2016 Interim efficacy and safety from a phase I trial in Solid tumours were presented at 41st European Society for Medical Oncology Congress (ESMO-2016)
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