Research programme: antibody therapeutics - Enumeral Biomedical

Drug Profile

Research programme: antibody therapeutics - Enumeral Biomedical

Alternative Names: 244C8; 388D4; Allosteric anti-PD-1 antibodies - Enumeral; ENUM 244C8; ENUM005; ENUM008; ENUM009

Latest Information Update: 21 Nov 2016

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At a glance

  • Originator Enumeral Biomedical Holdings; University of Texas M. D. Anderson Cancer Center
  • Developer Enumeral Biomedical Holdings
  • Class Antibodies
  • Mechanism of Action CD223 antigen inhibitors; Checkpoint kinase inhibitors; HAVCR2 protein inhibitors; OX40 ligand inhibitors; PDCD 1 protein inhibitors; TIGIT protein inhibitors; VISTA inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Preclinical Cancer
  • Research Inflammation

Most Recent Events

  • 10 Nov 2016 Antibody therapeutics from Enumeral Biomedical are available for licensing as of 10 Nov 2016.
  • 15 Jul 2016 Pharmacodynamics and safety data from a preclinical study presented at the 107th Annual Meeting of the American Association for Cancer Research (AACR-2016)
  • 06 Jun 2016 Pieris Pharmaceuticals in-licenses anti-PD-1 antibody program from Enumeral Biomedical
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