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Research programme: macrocyclic peptide therapeutics - Circle Pharma

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Drug Profile

Research programme: macrocyclic peptide therapeutics - Circle Pharma

Alternative Names: Cancer therapeutics - Circle Pharma; CyclinA/Cdk2-targeting molecules - Circle Pharma; MCL1-targeting molecules - Circle Pharma

Latest Information Update: 28 Feb 2024

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At a glance

  • Originator Circle Pharma
  • Developer Circle Pharma; Pfizer
  • Class Antineoplastics; Macrocyclic compounds; Peptides
  • Mechanism of Action CXCR7 protein modulators; Cyclin inhibitors; Cyclin-dependent kinase 2 modulators; Intracellular signalling peptide and protein inhibitors; MCL1 protein modulators; Protein-protein interaction inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 28 Feb 2024 No recent reports of development identified for preclinical development in Cancer in USA (PO)
  • 09 Oct 2023 Pharmacodynamics data from a preclinical trial in Cancer released by Circle Pharma
  • 22 Dec 2022 Circle Pharma plans a IND enabling studies for Cancer in 2023 (PO).
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