ACE 083

Drug Profile

ACE 083

Alternative Names: ACE-083

Latest Information Update: 17 Nov 2017

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At a glance

  • Originator Acceleron Pharma
  • Class Recombinant fusion proteins
  • Mechanism of Action TGF-beta superfamily protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Charcot-Marie-Tooth disease; Facioscapulohumeral muscular dystrophy
  • Discontinued Inclusion body myositis

Most Recent Events

  • 17 Nov 2017 Discontinued - Preclinical for Inclusion body myositis in USA (IM)
  • 25 Apr 2017 Phase-II clinical trials in Charcot-Marie-Tooth disease (In adults, In the elderly) in USA (IM) (NCT03124459)
  • 16 Mar 2017 Acceleron plans a phase II trial in Charcot-Marie-Tooth disease (Parenteral)
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