Research programme: retinoic acid receptor gamma agonists - Lycera

Drug Profile

Research programme: retinoic acid receptor gamma agonists - Lycera

Alternative Names: ACT therapy - Lycera; Adoptive T cell transfer therapy - Lycera; RORgamma agonist - Lycera; RORγ agonists - Lycera

Latest Information Update: 28 Apr 2016

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At a glance

  • Originator Lycera
  • Class Antineoplastics; Cell therapies; Small molecules
  • Mechanism of Action Cell replacements; Immunostimulants; Nuclear receptor subfamily 1 group F member 3 agonists; Retinoic acid receptor gamma agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Breast cancer; Cancer; Colorectal cancer

Most Recent Events

  • 19 Apr 2016 Interim pharmacodynamics data from a Preclinical study in Cancer presented at the 107th Annual Meeting of the American Association for Cancer Research (AACR-2016)
  • 11 Jan 2016 Retinoic acid receptor gamma agonists licensed to Celgene
  • 09 Jun 2015 Lycera and Celgene agree to co-develop Retinoic acid receptor gamma agonists worldwide
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