Research programme: cancer immunotherapeutics - Pfizer

Drug Profile

Research programme: cancer immunotherapeutics - Pfizer

Alternative Names: Anti-CD134 monoclonal antibody - Pfizer; Anti-CD3 anti-BCMA bispecific antibody; Anti-macrophage colony stimulating factor antibody- Pfizer; anti-MCSF-antibody- Pfizer; Anti-OX40 monoclonal antibody - Pfizer; Anti-PD1 monoclonal antibody - Pfizer; CCR2-inhibitor- Pfizer; PF-06863135; Prostate cancer vaccine - Pfizer

Latest Information Update: 14 Feb 2017

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At a glance

  • Originator Pfizer
  • Class Bispecific antibodies; Cancer vaccines; Monoclonal antibodies
  • Mechanism of Action Immunostimulants; OX40 receptor antagonists; PDCD 1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer; Prostate cancer

Most Recent Events

  • 06 Sep 2017 Pfizer plans a phase I trial of PF 06863135 for Multiple myeloma (Refractory metastatic disease, Late-stage disease, Second-line therapy or greater) (NCT03269136)
  • 03 Dec 2016 Pharmacodynamics data from preclinical studies in Cancer presented at the 58th Annual Meeting and Exposition of the American Society of Hematology (ASH-Hem-2016)
  • 19 Nov 2014 Pfizer and Merck KGaA enter into a collaboration to advance Pfizer's anti-PD1 antibody into phase I trials
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