PT 2385

Drug Profile

PT 2385

Alternative Names: PT-2385

Latest Information Update: 06 Dec 2016

Price : $50

At a glance

  • Originator University of Texas Southwestern Medical Center
  • Developer Peloton Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Endothelial PAS domain-containing protein 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Renal cell carcinoma
  • Preclinical Glioblastoma; Von Hippel-Lindau disease

Most Recent Events

  • 06 Dec 2016 Preclinical trials in Glioblastoma in USA (PO) before December 2016
  • 06 Dec 2016 Preclinical trials in Von Hippel-Lindau disease in USA (PO) before December 2016
  • 06 Jun 2016 Initial positive efficacy, pharmacodynamic and adverse events data from a phase I trial in Renal cell carcinoma presented at the 52nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2016)
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