Drug Profile
Anti-CD19 chimeric antigen receptor T cell therapy - Takara Bio
Alternative Names: CD19 CAR gene transduced T lymphocytes - Takara Bio; CD19 chimeric antigen receptor T cell therapy - Takara Bio; CD19-CAR gene therapy - Takara Bio; CD19-CAR T cell therapy - Takara Bio; TBI-1501Latest Information Update: 17 Nov 2021
Price :
$50
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At a glance
- Originator Memorial Sloan-Kettering Cancer Center
- Developer Jichi Medical School; Otsuka Pharmaceutical; Takara Bio
- Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II Non-Hodgkin's lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma
Most Recent Events
- 09 Nov 2021 Otsuka Pharmaceutical terminates development and licensing agreement with Takara Bio for anti-CD19 chimeric antigen receptor T cell therapy in Japan
- 10 Apr 2018 Otsuka Pharmaceutical and Takara Bio agree to co-promote [and co-develop] TBI 1301 in Japan for Cancer
- 19 May 2017 Takara Bio plans a phase I/II trial for Acute lymphoblastic leukaemia (Second-line therapy or greater) in Japan (NCT03155191)