GDC 0276

Drug Profile

GDC 0276

Alternative Names: GDC-0276; RG-7893

Latest Information Update: 06 Mar 2017

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At a glance

  • Originator Xenon Pharmaceuticals
  • Developer Genentech; Xenon Pharmaceuticals
  • Class Non-opioid analgesics; Small molecules
  • Mechanism of Action Nav1.7-voltage-gated-sodium-channel-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Pain

Most Recent Events

  • 24 Feb 2017 Genentech withdraws prior to enrolment a phase I bioavailability trial in Healthy volunteers in United Kingdom (NCT02856152)
  • 08 Jan 2017 Genentech completes a phase I trial in Pain (In volunteers) in Canada (PO)
  • 15 Mar 2016 Xenon Pharmaceuticals and Genentech extends its agreement to co-develop GDC 0276 for Pain
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