Drug Profile


Alternative Names: Antibody-coupled T-cell receptor anti-CD20 immunotherapy - Unum-Therapeutics; ATTCK20; mRNA ACTR T-cells + rituximab

Latest Information Update: 10 Feb 2017

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At a glance

  • Originator Unum Therapeutics
  • Developer National University Hospital (Singapore); Singapore General Hospital; Unum Therapeutics
  • Class Immunotherapies; Monoclonal antibodies; T lymphocyte cell therapies
  • Mechanism of Action B cell inhibitors; CD20 antigen inhibitors; Immunostimulants; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 03 Dec 2016 Efficacy and Adverse events data from a phase I trial in Chronic lymphocytic leukaemia (Second-line therapy or greater) presented at the 58th Annual Meeting and Exposition of the American Society of Hematology
  • 14 Dec 2015 Unum Therapeutics plans a phase I trial for Non-Hodgkin lymphoma (Second-line therapy or greater) in USA
  • 01 Dec 2014 Phase-I clinical trials in Chronic lymphocytic leukaemia (Second-line therapy or greater) in Singapore (Parenteral)
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