Drug Profile


Alternative Names: BCX-4430

Latest Information Update: 02 Jan 2017

Price : $50

At a glance

  • Originator BioCryst Pharmaceuticals
  • Developer BioCryst Pharmaceuticals; National Institute of Allergy and Infectious Diseases; Utah State University
  • Class Antivirals; Purine nucleosides; Pyrimidine nucleosides; Pyrroles; Pyrrolidines; Small molecules
  • Mechanism of Action RNA replicase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Ebola virus infections; Marburg virus disease
  • Preclinical Middle East respiratory syndrome coronavirus; Yellow fever; Zika virus infection

Most Recent Events

  • 26 Oct 2016 Preclinical data from a in Zika virus infection presented at the IDWeek 2016 (IDW - 2016)
  • 26 Oct 2016 Pharmacodynamics data from a preclinical study in Zika virus infections released by BioCryst Pharmaceuticals
  • 07 Sep 2016 Pharmacodynamics data from a preclinical study in Ebola virus infections released by BioCryst Pharmaceuticals
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