Drug Profile


Alternative Names: anti-HPV E6 TCR; anti-HPV-16 E6 TCR; HPV-16 E6 TCR

Latest Information Update: 21 Apr 2016

Price : $50

At a glance

  • Originator Kite Pharma; National Cancer Institute (USA)
  • Class Cell therapies; Gene therapies; T lymphocyte cell therapies
  • Mechanism of Action Gene transference; Human papillomavirus E6 T cell receptor expression modulators; T-cell receptor antigen antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Anal cancer; Cervical cancer; Oropharyngeal cancer; Penile cancer; Vulvovaginal cancer

Most Recent Events

  • 09 Apr 2016 National Cancer Institute suspends patients enrolment in a phase II trial for Cervical, Vulvovaginal, Penile, Anal and Oropharyngeal cancer (Late-stage disease, Second-line therapy or greater) in USA (NCT02280811)
  • 27 Oct 2015 HPV-16 E6 TCR added to synonyms
  • 31 Oct 2014 Phase-II clinical trials in Cervical cancer (Late-stage disease, Second-line therapy or greater) in USA (IV)
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