Research programme: anti-cancer therapeutics - Aurigene/Curis

Drug Profile

Research programme: anti-cancer therapeutics - Aurigene/Curis

Alternative Names: AUPM-170; AUPM-327; CA 327; PD-L1 antagonists - Aurigene/Curis; PD-L1/TIM-3 antagonists - Aurigene/Curis; PD-L1/VISTA antagonists - Aurigene/Curis; Programmed death ligand-1 antagonists - Aurigene/Curis

Latest Information Update: 13 Oct 2016

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At a glance

  • Originator Aurigene Discovery Technologies
  • Class Small molecules
  • Mechanism of Action CD274 antigen inhibitors; HAVCR2 protein inhibitors; VISTA inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 07 Nov 2017 Curis announces intention to submit IND application of CA 327 to the US FDA in first half of 2018
  • 11 Oct 2016 Curis exercises its option to exclusively license small molecule antagonists of programmed death ligand-1 (PD-L1) and T-cell immunoglobulin and mucin domain containing protein-3 (CA 327)
  • 11 Oct 2016 Aurigene announces intention to submit IND for CA 327 in 2017
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