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BAY 1128688

Drug Profile

BAY 1128688

Alternative Names: BAY-1128688

Latest Information Update: 25 Feb 2021

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At a glance

  • Originator Bayer HealthCare
  • Class
  • Mechanism of Action AKR1C3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Endometriosis

Most Recent Events

  • 30 Nov 2020 Discontinued - Phase-I for Endometriosis (In volunteers) in Germany (PO) (Bayer pipeline, November 2020)
  • 30 Nov 2020 Discontinued - Phase-II for Endometriosis in United Kingdom, Poland, Netherlands, Italy, Hungary, Germany, France, Finland, Denmark, Czech Republic, Belgium, Austria, Spain (PO) (Bayer pipeline, November 2020)
  • 20 Jul 2018 Bayer terminates the phase II AKRENDO1 trial in Endometriosis in Austria, Belgium, Czech Republic, Denmark, Finland, France, Germany, Hungary, Italy, Netherlands, Poland, Spain and United Kingdom due to hepatotoxicity (NCT03373422) (EudraCT2017-000244-18)
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