Drug Profile


Alternative Names: M-2951; MSC 2364447; MSC2364447C

Latest Information Update: 16 Jun 2017

$50 / €47 *
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At a glance

  • Originator Merck Serono
  • Class Antirheumatics; Piperidines; Pyrimidines; Small molecules
  • Mechanism of Action Agammaglobulinaemia tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Multiple sclerosis; Rheumatoid arthritis; Systemic lupus erythematosus
  • Phase I Autoimmune disorders

Most Recent Events

  • 25 Jul 2017 EMD Serono and Merck plan a phase IIb trial for Rheumatoid arthritis (In adults, In the elderly) in USA and Germany (PO) (NCT03233230)
  • 16 Jun 2017 Chemical structure information added
  • 16 Feb 2017 Phase-II clinical trials in Multiple sclerosis in Slovakia, Spain, Germany, Czech Republic (PO) (NCT02975349; EudraCT2016-001448-21)
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