MCLA 128

Drug Profile

MCLA 128

Alternative Names: MCLA-128

Latest Information Update: 31 May 2017

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At a glance

  • Originator Merus
  • Class Antineoplastics; Bispecific antibodies
  • Mechanism of Action ERBB 2 receptor antagonists; ERBB-3 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 19 Sep 2017 Merus plans a phase II trial for Breast cancer (Metastatic disease, Combination therapy, Chemotherapy-induced) in USA and Europe in fourth quarter of 2017
  • 17 May 2017 Updated efficacy and adverse events data from a phase I/II trial in Solid tumours released by Merus
  • 01 Apr 2017 Pharmacodynamics data from a phase I/II trial in Solid tumours presented at the 108th Annual Meeting of the American Association for Cancer Research
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