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Research programme: kinase-inhibiting RNase attenuators - OptiKira

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Drug Profile

Research programme: kinase-inhibiting RNase attenuators - OptiKira

Alternative Names: Cell death inhibitors - OptiKira; ERN1 protein inhibitors - OptiKira; Small molecule therapeutics - OptiKira

Latest Information Update: 28 Feb 2024

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At a glance

  • Originator OptiKira
  • Developer Charles River Laboratories; OptiKira
  • Class Antifibrotics; Antihyperglycaemics; Eye disorder therapies; Hepatoprotectants; Neuroprotectants; Small molecules
  • Mechanism of Action Cell death inhibitors; ERN1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Amyotrophic lateral sclerosis; Diabetes mellitus; Hepatic fibrosis; Pulmonary fibrosis; Retinitis pigmentosa

Most Recent Events

  • 28 Feb 2024 No recent reports of development identified for preclinical development in Hepatic-fibrosis in USA (Parenteral)
  • 28 Feb 2024 No recent reports of development identified for preclinical development in Pulmonary-fibrosis in USA (Parenteral)
  • 28 Jun 2022 No recent reports of development identified for preclinical development in Amyotrophic-lateral-sclerosis in USA (Parenteral)
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