ALRN 6924

Drug Profile

ALRN 6924

Alternative Names: ALRN6924

Latest Information Update: 09 Jul 2017

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At a glance

  • Originator Aileron Therapeutics; Roche
  • Developer Aileron Therapeutics
  • Class Antineoplastics; Peptides
  • Mechanism of Action Proto-oncogene protein c mdm2 inhibitors; Tumour suppressor protein p53 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Haematological malignancies; Solid tumours
  • Phase I Acute myeloid leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 02 Jun 2017 Interim safety and efficacy data from a phase I trial in Solid tumours and Haematological malignancies presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017) (3249351; 9220495)
  • 18 May 2017 ALRN 6924 receives Orphan Drug status for Acute myeloid leukaemia in USA
  • 09 Sep 2016 Phase-I clinical trials in Acute myeloid leukaemia (Second-line therapy or greater) in USA (IV) (NCT02909972)
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