BAY 1238097

Drug Profile

BAY 1238097

Alternative Names: BAY-1238097; BET inhibitor

Latest Information Update: 29 Dec 2016

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At a glance

  • Originator Bayer
  • Class Antineoplastics
  • Mechanism of Action Bromodomain and extraterminal domain protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Lymphoma; Solid tumours
  • Preclinical Cancer; Haematological malignancies

Most Recent Events

  • 29 Nov 2016 Adverse events and pharmacokinetics data from a phase I trial in Solid tumours and lymphoma presented at the 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
  • 07 Apr 2016 Pharmacodynamics data from preclinical and in vitro studies in Melanoma and Lung cancer presented at the 107th Annual Meeting of American Association for Cancer Research (AACR-2016) (3182732; 3182741)
  • 26 Feb 2016 Bayer terminates a phase I trial in Lymphoma and Solid tumours (Late-stage disease) in United States, United Kingdom, France, Finland, Germany and Switzerland (NCT02369029)
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