IW 1973

Drug Profile

IW 1973

Alternative Names: IW1973; sGC agonist-Ironwood

Latest Information Update: 10 Nov 2017

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At a glance

  • Originator Ironwood Pharmaceuticals
  • Class Cardiovascular therapies
  • Mechanism of Action Soluble guanylyl cyclase agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cardiovascular disorders; Diabetic nephropathies; Heart failure; Hypertension in diabetes
  • Phase I Pulmonary arterial hypertension

Most Recent Events

  • 02 Nov 2017 Phase-II clinical trials in Diabetic nephropathy in USA (PO)
  • 02 Nov 2017 Phase-II clinical trials in Heart failure in USA (PO)
  • 14 Sep 2017 Adverse events and pharmacokinetics data from a phase Ib trial in healthy volunteers presented at the Council on Hypertension Scientific Session 2017 (AHA-ASH-2017)
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