Drug Profile


Alternative Names: PLX R 18; PLX RAD

Latest Information Update: 15 Sep 2017

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At a glance

  • Originator Hadassah Medical School; Pluristem Therapeutics
  • Developer Case Western Reserve University; Hadassah Medical School; National Institute of Allergy and Infectious Diseases; Pluristem Therapeutics
  • Class Stem cell therapies
  • Mechanism of Action Bone marrow cell stimulants; Cell differentiation modulators; Cell replacements; Stem cell modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Aplastic anaemia
  • New Molecular Entity No

Highest Development Phases

  • Phase I Aplastic anaemia; Graft-versus-host disease
  • Preclinical Acute radiation syndrome

Most Recent Events

  • 13 Sep 2017 Pluristem Therapeutics has patent protection for placental expanded (PLX) cells for the treatment of Critical limb ischaemia and muscle regeneration in Hong Kong
  • 17 Aug 2017 US Department of Defense plans a pilot preclinical study for PLX R18 for Acute radiation syndrome
  • 03 May 2017 Pharmacodynamics data from a preclinical study in Acute radiation syndrome released by Pluristem therapeutics
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