Research programme: hexokinase II inhibitors - Calithera Biosciences/vTv Therapeutics

Drug Profile

Research programme: hexokinase II inhibitors - Calithera Biosciences/vTv Therapeutics

Latest Information Update: 06 Apr 2016

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At a glance

  • Originator TransTech Pharma
  • Developer vTv Therapeutics LLC
  • Class Small molecules
  • Mechanism of Action Glycolysis inhibitors; Hexokinase inhibitors; Small interfering RNA inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 15 Mar 2016 Calithera Biosciences has patents pending directed to compositions of matter for hexokinase II inhibitors and therapeutic methods of using the compounds in USA (Calithera Biosciences, 10-K, March 2016)
  • 20 Mar 2015 Preclinical trials in Cancer in USA (unspecified route)
  • 05 Mar 2015 Hexokinase II inhibitors licensed to Calithera Biosciences worldwide for the treatment of Cancer
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