Ivacaftor deuterated

Drug Profile

Ivacaftor deuterated

Alternative Names: C-10355; C-10358; CTP-656; D-ivacaftor; Deuterated ivacaftor; VX 561

Latest Information Update: 21 Sep 2017

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At a glance

  • Originator Concert Pharmaceuticals
  • Class Amides; Aminophenols; Organic deuterium compounds; Quinolones; Small molecules
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cystic fibrosis

Most Recent Events

  • 08 Aug 2017 Chemical structure information added
  • 01 Aug 2017 Vertex Pharmaceuticals terminates a phase II trial in Cystic fibrosis in USA (PO) (NCT02971839)
  • 25 Jul 2017 Vertex Pharmaceuticals purchases ivacaftor deuterated from Concert Pharmaceuticals
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