Research programme: enzyme therapeutics - Aeglea Biotherapeutics

Drug Profile

Research programme: enzyme therapeutics - Aeglea Biotherapeutics

Alternative Names: AEB 2109; AEB 3103; AEB 4104; AECase/AEB3103; AEMase/AEB2109

Latest Information Update: 30 Nov 2016

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At a glance

  • Originator Aeglea Biotherapeutics
  • Class Antineoplastics; Enzymes
  • Mechanism of Action Enzyme replacements; Neutral amino acid inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Haematological malignancies; Homocystinuria; Solid tumours

Most Recent Events

  • 03 May 2017 Aeglea Biotherapeutics announces intention to submit IND to US FDA for Solid tumours, Homocystinuria and Haematological malignancies in 2018
  • 21 Nov 2016 Pharmacodynamics data from a preclinical trial for AEB 3103 in Solid tumours and Haematological malignancies released by Aeglea Biotherapeutics
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