Drug Profile


Alternative Names: Cancer vaccine - Annias Immunotherapeutics; Cytomegalovirus vaccine - Annias Immunotherapeutics; Cytomegalovirus-specific peptide vaccine - Annias Immunotherapeutics; Dendritic cell vaccine - Annias Immunotherapeutics; PEP CMV

Latest Information Update: 17 Aug 2016

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At a glance

  • Originator Duke University
  • Class Cancer vaccines; Dendritic cell vaccines; Peptide vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Glioblastoma

Most Recent Events

  • 03 Oct 2017 Pediatric Brain Tumor Foundation and Annias Immunotherapeutics plan the phase I PRiME trial for Medulloblastoma (Recurrent, Second-line therapy or greater, In children, In adolescents) and malignant Glioma (Recurrent, Late-stage disease, Second-line therapy or greater, In children, In adolescents) in USA (Intradermal, Injection) (NCT03299309)
  • 10 Aug 2016 Annias Immunotherapeutics, Duke University Medical Center, National Cancer Institute and National Institutes of Health plan the phase I PERFORMANCE trial for Glioblastoma (Combination therapy, Newly diagnosed) in USA (Intradermal) (NCT02864368)
  • 10 Apr 2015 Duke University plans a phase I trial for Glioblastoma (Combination therapy, Recurrent, Early-stage disease) in USA (NCT02193347)
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