GS 0976

Drug Profile

GS 0976

Alternative Names: GS-0976; NDI 010976

Latest Information Update: 18 Aug 2017

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At a glance

  • Originator Nimbus Therapeutics
  • Developer Gilead Sciences; Nimbus Therapeutics
  • Class Small molecules
  • Mechanism of Action Acetyl-CoA carboxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis

Most Recent Events

  • 08 Aug 2017 Nimbus Therapeutics completes a phase II trial for Non-alcoholic steatohepatitis in USA (NCT02856555)
  • 21 Apr 2017 Adverse events and pharmacodynamics data from phase II trial in Non-alcoholic steatohepatitis presented at the The International Liver Congress™ 2017 of the European Association for the Study of the Liver (EASL-2017)
  • 19 Apr 2017 Phase-I clinical trials in Non-alcoholic steatohepatitis (In volunteers, Combination therapy) in USA (PO) before April 2017
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