Drug Profile


Alternative Names: ADXS-PSA; ADXS31-142; Live attenuated Listeria-based vaccines for cancer - Advaxis; Lovaxin P; Prostate cancer vaccine - Advaxis

Latest Information Update: 23 Aug 2017

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At a glance

  • Originator Advaxis
  • Developer Advaxis; Merck & Co
  • Class Cancer vaccines; Recombinant fusion proteins
  • Mechanism of Action Immunostimulants; Kallikrein inhibitors; Tumour protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Prostate cancer

Most Recent Events

  • 13 Jun 2017 Efficacy data from a phase-I/II clinical trial in Prostate cancer released by Advaxis
  • 13 Jun 2017 Advaxis plans to initiate an investigator sponsored trial for Prostate cancer in unknown countries
  • 20 Oct 2016 Advaxis initiates enrolment in the KEYNOTE-046 trial for Prostate cancer (Combination therapy, Hormone refractory, Metastatic disease) in USA (NCT02325557)
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