Drug Profile


Alternative Names: Trimethobenzamide/diphenhydramine

Latest Information Update: 27 Jan 2016

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At a glance

  • Originator Multi-Corp International
  • Developer Compass Point Research; NDA Partners
  • Class Antiallergics; Antiemetics; Antimigraines; Antipruritics; Sedating antihistamines
  • Mechanism of Action Histamine H1 receptor antagonists; Muscarinic receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Research Migraine

Most Recent Events

  • 21 Jan 2016 MultiCorp International receives detailed response letter from the FDA for development of diphenhydramine/trimethobenzamide in Migraine
  • 08 Apr 2015 MultiCorp International collaborates with Compass Point and NDA Partners to develop diphenhydramine/trimethobenzamide for the treatment of migraine
  • 08 Apr 2015 Early research in Migraine in USA (Parenteral)
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