Drug Profile


Alternative Names: DPX-E7; HPV16-E711-19

Latest Information Update: 11 Apr 2017

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At a glance

  • Originator Immunovaccine
  • Developer Dana-Farber Cancer Institute; Immunovaccine; Peregrine Pharmaceuticals
  • Class Cancer vaccines; Viral vaccines
  • Mechanism of Action Human papillomavirus E7 protein modulators; Viral oncogene protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Anal cancer; Cervical cancer; Head and neck cancer
  • Preclinical Solid tumours

Most Recent Events

  • 11 Apr 2017 Pharmacodynamics data from the preclinical trials presented at the American Association for Cancer Research annual meeting 2017 (AACR-2017)
  • 24 Mar 2017 Preclinical trials in Solid tumours (Combination therapy) in USA (unspecified route)
  • 21 Oct 2016 Phase-I/II clinical trials in Anal cancer, Cervical cancer and Head and neck cancer (Combination therapy) in USA (SC)
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