REMD 477

Drug Profile

REMD 477

Alternative Names: AMG477; REMD477

Latest Information Update: 20 Sep 2017

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At a glance

  • Originator Amgen
  • Developer REMD Biotherapeutics
  • Class Antibodies; Antihyperglycaemics
  • Mechanism of Action Glucagon receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Type 1 diabetes mellitus; Type 2 diabetes mellitus
  • Preclinical Metabolic disorders

Most Recent Events

  • 17 Aug 2017 Phase-II clinical trials in Type-1 diabetes mellitus (Treatment-experienced) in USA (SC) (NCT03117998)
  • 13 Jun 2017 Efficacy data from a phase I trial in Type 1 diabetes mellitus presented at the 77th Annual Scientific Sessions of the American Diabetes Association (ADA-2017)
  • 20 Apr 2017 REMD Biotherapeutics plans a phase II trial for Type-1 diabetes mellitus (Treatment-experienced) in USA (SC) (NCT03117998)
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