JNJ 54175446

Drug Profile

JNJ 54175446

Alternative Names: JNJ-54175446

Latest Information Update: 13 Jul 2017

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At a glance

  • Originator Janssen-Cilag
  • Class Antidepressants; Azoles; Phenols; Pyridines; Pyrimidines
  • Mechanism of Action Purinergic P2X7 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Major depressive disorder

Most Recent Events

  • 02 Jun 2017 Janssen Research & Development completes a phase I trial in Major depressive disorder in Germany and the Netherlands (PO) (NCT02902601)
  • 15 May 2017 Janssen completes a phase I trial in Major depressive disorder (In volunteers) in Belgium (PO) (NCT03058419)
  • 21 Apr 2017 Chemical structure information added
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