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Efzofitimod - aTyr Pharma

Drug Profile

Efzofitimod - aTyr Pharma

Alternative Names: ATY 1923; ATYR-1923; iMod.Fc; KRP-R120; Stalaris

Latest Information Update: 20 Mar 2024

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At a glance

  • Originator aTyr Pharma
  • Developer aTyr Pharma; Foundation for Sarcoidosis Research; Kyorin Pharmaceutical
  • Class Anti-inflammatories; Antifibrotics; Antirheumatics; Antivirals; Immunoglobulin Fc fragments; Proteins; Recombinant fusion proteins
  • Mechanism of Action Neuropilin-2 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Systemic scleroderma; Sarcoidosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Pulmonary sarcoidosis
  • Phase II COVID-19 pneumonia; Interstitial lung diseases
  • Preclinical Rheumatoid arthritis
  • No development reported Pulmonary fibrosis

Most Recent Events

  • 14 Mar 2024 aTyr Pharma announces intention to file Biologics License Application (BLA) for efzofitimod in pulmonary sarcoidosis
  • 14 Mar 2024 aTyr Pharma initiates an Individual Patient Expanded Access Program (EAP) for Pulmonary sarcoidosis (In adults, In the elderly, Treatment-experienced) (IV, Infusion)
  • 21 Feb 2024 aTyr Pharma plans Individual Patient Expanded Access Program (EAP) for Pulmonary sarcoidosis (In adults, In the elderly, Treatment-experienced) (IV, Infusion)
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