Drug Profile


Alternative Names: Cilastatin/relebactam/imipenem; IMI/REL; Imipenem/cilastatin/relebactam; Imipenem/relebactam/cilastatin; MK 7655; MK-7655 + cilastatin/imipenem; MK-7655 + imipenem/cilastatin; MK-7655A; Relebactam + imepenem/cilastatin; Relebactam/cilastatin/imipenem; Relebactam/imipenem/cilastatin

Latest Information Update: 21 Mar 2017

Price : $50

At a glance

  • Originator Merck Sharp & Dohme
  • Class Antibacterials; Azabicyclo compounds; Carbapenems; Cyclopropanes; Piperidines; Small molecules; Thienamycins
  • Mechanism of Action Beta lactamase inhibitors; Cell wall inhibitors; Exopeptidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase III Bacterial infections; Pneumonia

Most Recent Events

  • 28 Feb 2017 Merck has patent protection for cilastatin/relebactam/imipenem in USA (Merck Annual report 2016)
  • 20 Jun 2016 Interim efficacy and adverse events data from a phase II trial in bacterial infections released by Merck
  • 24 Dec 2015 Phase-III clinical trials in Pneumonia in South Korea (IV) (NCT02493764)
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