AG 881

Drug Profile

AG 881

Alternative Names: AG-881

Latest Information Update: 23 Jul 2015

Price : $50

At a glance

  • Originator Agios Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Isocitrate dehydrogenase 1 inhibitors; Isocitrate dehydrogenase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Glioma; Haematological malignancies; Solid tumours

Most Recent Events

  • 01 Jul 2015 Phase-I clinical trials in Haematological malignancies (Late-stage disease) in USA (PO) (NCT02492737)
  • 01 Jun 2015 Phase-I clinical trials in Glioma (Late-stage disease, Second-line therapy or greater) in USA (PO) (NCT02481154)
  • 01 Jun 2015 Phase-I clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater) in USA (PO) (NCT02481154)
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