Drug Profile


Alternative Names: Ad MAGEA3; Marabex; MG1 Maraba/MAGE-A3; MG1-MAGEA3; MG1MA3

Latest Information Update: 13 Oct 2017

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At a glance

  • Originator Children's Hospital of Eastern Ontario; McMaster University; University of Ottawa
  • Developer National Cancer Institute (Canada); Turnstone Biologics
  • Class Cancer vaccines; Oncolytic viruses
  • Mechanism of Action Immunostimulants; Neoplasm antigen modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 10 Oct 2017 AbbVie enters into an option license agreement with Turnstone Biologics for its oncolytic viral immunotherapies
  • 02 Jun 2017 Preliminary efficacy and adverse events data from a phase I/II trial in Solid tumours presented at the 53rd Annual Meeting of the American Society of Clinical Oncology
  • 01 Dec 2016 Phase-I/II clinical trials in Solid tumours (Combination therapy, Second-line therapy or greater) in Canada (IV) (NCT02879760)
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