Coversin

Drug Profile

Coversin

Alternative Names: EV 576; PAS-coversin; rEV 576; Tissue targeted Coversin™ - Akari

Latest Information Update: 06 Jan 2017

Price : $50

At a glance

  • Originator Evolutec
  • Developer Akari Therapeutics; Evolutec
  • Class Anti-inflammatories; Recombinant proteins
  • Mechanism of Action Complement C5 inhibitors; Leukotriene B4 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Paroxysmal nocturnal haemoglobinuria; Guillain-Barre syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Paroxysmal nocturnal haemoglobinuria
  • Preclinical Guillain-Barre syndrome; Haemolytic uraemic syndrome; Myasthenia gravis; Sjogren's syndrome
  • Discontinued Asthma; Autoimmune disorders; Inflammation

Most Recent Events

  • 05 Jan 2017 Akari Therapeutics plans a phase III trial for Paroxysmal nocturnal haemoglobinurea
  • 04 Jan 2017 Preclinical trials of tissue targeted form of Coversin™ in Myasthenia gravis in United Kingdom (unspecified route)
  • 29 Dec 2016 US FDA grants allowance for its IND of coversin to expand ongoing phase II trial in Paroxysmal nocturnal haemoglobinuria to the US
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