Research programme: metalloprotein inhibitors - Forge Therapeutics

Drug Profile

Research programme: metalloprotein inhibitors - Forge Therapeutics

Alternative Names: LpxC inhibitors - Forge Therapeutics; Metalloenzyme inhibitors - Forge Therapeutics

Latest Information Update: 06 Nov 2017

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At a glance

  • Originator Forge Therapeutics
  • Class Anti-infectives; Antineoplastics; Metalloproteins; Small molecules
  • Mechanism of Action Metalloprotein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Gram-negative infections
  • Research Cancer

Most Recent Events

  • 07 Sep 2017 Preclinical data in Gram-negative infections released by Forge Therapeutics and Evotec
  • 09 Dec 2016 Forge Therapeutics and Evotec agree to co-develop metalloprotein inhibitors for Gram-negative infections
  • 26 Jul 2016 Forge Therapeutics receives phase I SBIR grant from National Institute of Allergy and Infectious Diseases for Metalloprotein inhibitors development in Gram negative infections
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