Drug Profile


Alternative Names: Alpha-methyl-p-tyrosine; Metyrosine; ONO-5371

Latest Information Update: 15 Jun 2017

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At a glance

  • Originator Valeant Pharmaceuticals International
  • Developer Ono Pharmaceutical
  • Class Amino acids; Antihypertensives; Small molecules
  • Mechanism of Action Enzyme inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Pheochromocytoma

Most Recent Events

  • 15 Jun 2017 Chemical structure information added
  • 01 Apr 2017 Adverse events and efficacy data from a phase I/II trial in Pheochromocytoma and paraganglioma presented at the 99th Annual Meeting of the Endocrine Society (ENDO-2017)
  • 01 Jul 2015 Phase-I/II clinical trials in Phaeochromocytoma (In adolescents, In adults, In the elderly) in Japan (PO) (JapicCTI152999)
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